Precision PDMS & Metal Molds for Microneedle Fabrication
We manufacture sub-micron medical-grade PDMS silicone casting molds and diamond micro-machined 316L stainless steel / carbide metal master dies. Engineered specifically for university research scholars, biomedical labs, and pharmaceutical R&D teams to cast dissolving, polymeric, and hydrogel microneedles with sub-micron tip sharpness (< 5 µm).
Examples of Microneedles You Can Fabricate
Our PDMS silicone molds and metal master dies provide flawless surface finish and sub-micron sharpness for replicating all major classes of microneedle arrays.
1. Dissolving Hyaluronic Acid Arrays
Cast dissolving polymers (Hyaluronic Acid, Sodium Carboxymethyl Cellulose, PVA, PVP) to deliver peptides, vitamins, and cosmeceuticals that dissolve completely in skin interstitial fluid within 20 minutes.
- Dissolution: < 20 minutes in-skin
- Common Heights: 450 to 800 µm
- Centrifugal / vacuum casting ready
2. Biodegradable Polymeric Projections
Cast PLGA (poly-lactic-co-glycolic acid), polycaprolactone (PCL), or silk fibroin matrices for sustained, controlled therapeutic payload delivery of vaccines, insulin, or macromolecules over days or weeks.
- Controlled release: Hours to weeks
- High mechanical stability
- Thermal stability without cold-chain
3. Hydrogel-Forming ISF Arrays
Form crosslinked swellable hydrogels (GelMA, PEGDA, Poly-acrylic acid) for non-invasive interstitial fluid (ISF) sampling, continuous glucose monitoring, and rapid point-of-care biomarker detection.
- Swelling-based ISF extraction
- Zero sharps waste on removal
- High porosity and optical clarity
4. Solid & Coated Micro-Arrays
Molded from rigid biomedical polymers (PEEK, Polycarbonate, PMMA) for pre-treatment skin microporation or dip-coating with active vaccine antigens, peptides, and gene therapies.
- High insertion rigidity (> 0.15 N/needle)
- Dip-coating layer adhesion
- Ideal for difficult stratum corneum
Choose Your Tooling Medium
We manufacture both flexible silicone casting molds and permanent hard metal master plates.
Medical-Grade PDMS Silicone Molds
Ready-to-cast high-grade Polydimethylsiloxane (PDMS) negative molds. Engineered with high tensile elasticity to demold delicate micro-tips without cracking or plastic deformation. Compatible with standard laboratory centrifuge and vacuum degassing protocols.
- Optical transparency for bubble inspection under microscope
- Autoclavable and solvent-resistant surface passivation
- Standard Teflon backing plate for centrifuge buckets
Micro-Machined Metal Master Dies
Permanent positive metal master dies fabricated in 316L Stainless Steel, Brass, or Tungsten Carbide. Micro-machined with sub-micron diamond endmills to serve as the master standard for casting hundreds of PDMS molds in your own laboratory indefinitely.
- Hardened SS316L / Tungsten Carbide with mirror finish (Ra < 20 nm)
- Extreme tip sharpness preservation over infinite casting runs
- Supplied with full SEM metrology certificate and calibration data
Interactive Mold Geometry Configurator
Customize your needle shape, height, and array grid to calculate pitch, base dimensions, and active area for your research proposal.
Standard Laboratory Tooling Sets
Pre-validated mold sets for university research scholars, pharmaceutical labs, and thesis projects.
PDMS Standard 5-Pack
5 reusable PDMS silicone molds (650 µm pyramidal, 15x15 array) with Teflon backing carrier plates.
- 5 × PDMS Silicone Molds
- Teflon Centrifuge Base Carrier
- Standard Dissolving HA Casting SOP
University Complete 12-Pack
Includes 4 heights (350µm, 500µm, 650µm, 900µm) across pyramid and conical geometries for comparative skin permeation studies.
- 12 × Assorted PDMS Molds
- Dual Centrifuge Vacuum Holder
- Certificate of Conformance & SEM Data
Metal Master Plate + Self-Casting Kit
1 × 316L Stainless Steel Diamond-Turned Permanent Master Plate + Optical PDMS polymer kit to cast unlimited molds in your own laboratory.
- 316L Stainless Permanent Master Die
- Optical Grade PDMS Prepolymer Kit
- Vacuum Degassing Casting Fixture
Request a Custom Mold Proposal & Specs
We provide formal academic quotes, dimensional CAD drawings, and university PO invoices within 24 hours.